Expression of Glial Cell Line–Derived Neurotropic Factor Receptor α-1 in Immature Teratomas
نویسندگان
چکیده
منابع مشابه
Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor alpha1 expression.
Apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) dysregulation has been identified in several human tumors and in patients with a variety of neurodegenerative diseases. However, the function of Ape1/Ref-1 is unclear. We show here that Ape1/Ref-1 increases the expression of glial cell-derived neurotropic factor (GDNF) receptor alpha1 (GFRalpha1), a key receptor for GDNF. Expression of Ape1/Ref-...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2008
ISSN: 0002-9173,1943-7722
DOI: 10.1309/ajcplhc60zebajxa